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Research Professor of Chemistry
Ph.D. 1989, M.Sc. 1986, McGill; B.Sc. 1984, McMaster.
Email:
Research Interests: Computational RNA folding and design; modeling of RNA in vitro selection and evolution; applications of graph theory
Selected Works:
Kim N, Shin JS, Elmetwaly S, Gan HH, and Schlick T, RAGPOOLS:
RNA-As-Graph-Pools – A web server for assisting the design of
structured RNA pools for i n vitro s election. Bioinformatics 2007,
3(21):2959-60.
Kim N, Gan HH, Schlick T, A computational proposal for designing
structured RNA pools for in vitro selection of RNAs. RNA 2007,
13(4):478-92.
Gevertz J., Gan HH, and Schlick T, In vitro RNA random pools are not
structurally diverse: a computational analysis. RNA 2005, 11(6):853-63.
Laserson U, Gan HH, Schlick T, Predicting candidate genomic sequences
that correspond to synthetic functional RNA motifs. Nucleic Acids Res.
2005, 33(18):6057-69.
Pasquali S, Gan HH, Schlick T. Modular RNA architecture revealed by
computational analysis of existing pseudoknots and ribosomal RNAs.
Nucleic Acids Res. 2005, 33(4):1384-98.
Kim N, Shiffeldrim N, Gan HH, Schlick T. Candidates for novel RNA
topologies. J. Mol. Biol. 2004, 341(5):1129-44.
Gan HH, Fera D, Zorn J, Shiffeldrim N, Tang M, Laserson U, Kim N,
Schlick T. RAG: RNA-As-Graphs database--concepts, analysis, and
features. Bioinformatics. 2004, 20(8):1285-91.
Zorn J, Gan HH, Shiffeldrim N, Schlick T. Structural motifs in
ribosomal RNAs: implications for RNA design and genomics. Biopolymers.
2004, 73(3):340-7.
Gan HH, Pasquali S, Schlick T. Exploring the repertoire of RNA
secondary motifs using graph theory; implications for RNA design.
Nucleic Acids Res. 2003, 31(11):2926-43.
Gan HH, Tropsha A, Schlick T. Lattice protein folding with two and
four-body statistical potentials. Proteins. 2001, 43(2):161-74.
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