Assistant Professor of Biology
Ph.D., Edith Cowan University, Perth, Australia, Human Genetics, 2001; B.S., McGill University, Montreal, Canada, Biochemistry, 1997

Email:

Research Interests:

Genomics of adaptive evolution, growth-rate regulation and post-transcriptional gene regulation.

Publications

• A molecular barcoded yeast ORF library enables mode-of-action analysis of bioactive compounds.
  Nat Biotechnol
  Ho CH, Magtanong L, Barker SL, Gresham D, Nishimura S, Natarajan P, Koh JL, Porter J, Gray CA, Andersen RJ, Giaever G, Nislow C, Andrews B, Botstein D, Graham TR, Yoshida M, Boone C
  
  
• Predicting cellular growth from gene expression signatures.
  PLoS Comput Biol
  Airoldi EM, Huttenhower C, Gresham D, Lu C, Caudy AA, Dunham MJ, Broach JR, Botstein D, Troyanskaya OG
  
  
• The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast.
  PLoS Genet
  Gresham D, Desai MM, Tucker CM, Jenq HT, Pai DA, Ward A, DeSevo CG, Botstein D, Dunham MJ
  
  
• Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast.
  Mol Biol Cell
  Brauer MJ, Huttenhower C, Airoldi EM, Rosenstein R, Matese JC, Gresham D, Boer VM, Troyanskaya OG, Botstein D
  
  
• Genome-wide analysis of nucleotide-level variation in commonly used Saccharomyces cerevisiae strains.
  PLoS One
  Schacherer J, Ruderfer DM, Gresham D, Dolinski K, Botstein D, Kruglyak L
  
  
• Global mapping of transposon location.
  PLoS Genet
  Gabriel A, Dapprich J, Kunkel M, Gresham D, Pratt SC, Dunham MJ
  
  
• Accumulation of recessive lethal mutations in Saccharomyces cerevisiae mlh1 mismatch repair mutants is not associated with gross chromosomal rearrangements.
  Genetics
  Heck JA, Gresham D, Botstein D, Alani E
  
  
• Genome-wide detection of polymorphisms at nucleotide resolution with a single DNA microarray.
  Science
  Gresham D, Ruderfer DM, Pratt SC, Schacherer J, Dunham MJ, Botstein D, Kruglyak L
  
  

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